Você sobreviveu ao primeiro episódio? Ótimo. Neste você vai precisar, além do mesmo senso de humor esquisito, um controle magistral da tecla de "pause" do seu reprodutor.
O que você faria se o seu pai se casasse de novo... Com a mãe do gatão da escola que você gosta? Você viveria essa história de amor tórrido, ou se prenderia às amarras da sociedade? Se amor entre irmãos é errado, eu não quero estar certo.
Existem robôs programados para matar, robôs programados para amar, e robôs programados para não funcionar (impressoras). Mas estes robôs só querem jogar Shogi.
Musician Hellshake Yano is tasked with holding a concert by himself until his band members arrive. Other skits include dealing with haters, Popuko turning into a baby, and Pipimi going fishing.
Popuko and Pipimi encounter a young runaway boy while visiting New York City. Other skits include Popuko ordering latte art, Pipimi attempting standup comedy, and the girls trying French cuisine.
While staying at a hot spring inn, hostesses Popuko and Pipimi investigate a murder that has taken place. Other skits include the girls playing soccer, Pipimi cooking some premium meat, and Popuko dealing with incompetent waiters.
A group of college students find the mansion they are staying in to be haunted by Popuko and Pipimi. Other skits include Popuko starting a dance craze, Pipimi becoming giant, and Popuko going up against a shark.
Popuko and Pipimi have a final showdown against the evil organization trying to stop their anime, King Records. Other skits include a scene parodying magical girl anime tropes in which a girl brings a talking pet to school with her and Popuko trying to find her glasses. After the credits, there is a teaser trailer for a second season of Hoshiiro Girldrop.